substantificatrix Save DMLBS substantificatrix [substantificare+-trix], (for ὑποστάτις) that creates substance, ‘substantific’ (f.). totius esse ‥ ~ix causa Gros. Ps.-Dion. (Div. nom.) 332; omnisapiens causa ‥ et totius ‥ ~ix Ib. 388.